The team of Professor Jianping Jia from Xuanwu Hospital recently reported that there are more than 50 million people with cognitive impairment in China, and proposed that controlling risk factors can reduce the prevalence of dementia

In December 2020, the team of Professor Jianping Jia from Xuanwu Hospital published a paper in the Lancet Public Health (IF: 16.292), titled “Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study”. This study conducted an in-depth study on the prevalence, Read More …

Professor Jianping Jia’s team from Xuanwu Hospital discovered four new risk gene loci in China’s first large-sample Alzheimer’s disease whole-genome association analysis (GWAS) and constructed an incidence prediction model based on them

In November 2020, the team of Professor Jianping Jia from Xuanwu Hospital published a paper entitled “Prediction of Alzheimer’s disease using multi-variants from a Chinese genome-wide association study” in “Brain” (IF: 11.337).Through China’s first large-sample genome-wide association study (GWAS) study, four new risk gene loci related to Alzheimer’s disease (AD) were discovered. And using these Read More …

The Jia Jianping team of Xuanwu Hospital first proposed a biomarker method for the diagnosis of AD by replacing cerebrospinal fluid with peripheral blood exosomes

In Alzheimer’s disease(AD), the pathophysiological changes of brain Aβ and Tau occur 15 to 20 years before the onset of symptoms. If the pathophysiological changes can be detected in time before symptoms appear, and corresponding intervention measures can be taken, this will help reduce the incidence and prevalence of AD. At present, the research of Read More …

Heavy research! Jia Jianping’s team first reported 15119 cases of Alzheimer’s disease risk genes and genetic intervention strategies in China

The first international report on the distribution and role of the Alzheimer’s disease risk gene APOEε4 in 15119 cases of Chinese population provides strong evidence for genetic counseling and precise intervention. In September 2020, the team of Professor Jia Jianping from Xuanwu Hospital of Capital Medical University published an online work entitled “The APOE-ε4 exerts Read More …

The team of Professor Jianping Jia from Xuanwu Hospital reported 404 Chinese Alzheimer’s disease families for the first time in the world and revealed important genetic mechanisms

In January 2020, the team of Professor Jianping Jia from Xuanwu Hospital published an online article titled “PSEN1, PSEN2 and APP mutations in 404 Chinese pedigrees with familial Alzheimer’s disease” in Alzheimer’s & Dementia(IF: 14.423). The study conducted a 17-year follow-up study on 404 families with Familial Alzheimer’s disease (FAD) in China, and revealed the Read More …

Great discovery! Alzheimer’s disease can be predicted 5 to 7 years before cognitive impairment

In August 2020, Professor Jianping Jia’s team from Xuanwu Hospital published an online article entitled “Blood neuro-exosomal synaptic proteins predict Alzheimer’s disease at the asymptomatic stage” in Alzheimer’s & Dementia (IF: 17.127).It is the first report in the world that a biomarker that can predict Alzheimer’s disease (AD) is found in peripheral blood 5 to Read More …

Jia Jianping team of Xuanwu Hospital discussed the current situation of Chinese dementia patients and proposed prevention and control strategies in The Lancet Neurology

In August 2019, Jia Jianping’s team of Xuanwu Hospital published an online article entitled “Dementia in China: epidemiology, clinical management, and research advances” in the top international medical journal “The Lancet Neurology” (5 years IF: 30.542). Through more than 20 years of in-depth research on people with dementia, the research team summarized the current situation Read More …