Jianping Jia CV

Professor Jia, Jianping., MD, PhD

Director of Innovation Center for Neurological Disorders, Honorary director of Department of Neurology of Xuanwu Hospital, Head of Department of Neurology of Capital Medical University, former Chairman of Neurology Committee of Chinese Medical Association, former Chairman of the Neurologist Society of Chinese Medical Doctor Association.

His research interests include mechanisms, peripheral markers, and therapeutic drug development in Alzheimer’s disease and related dementias. He identified the first Chinese Alzheimer’s disease pedigree and opened a new era of Alzheimer’s disease genetic research in China. He has established the Chinese Familial Alzheimer’s Network Cohort (CFAN) and has reported more than 90 gene variations, which provided Chinese data for the global Alzheimer’s disease genetic study. Prof. Jia has also established a Chinese cognition and aging (COAST) study cohort of more than 100,000 people. He continuously reported basic data, including the prevalence of dementia and mild cognitive impairment, and health economic data, which has provided a large database for global research on the occurrence and development of dementia. Prof. Jia has also identified several biomarkers that can predict Alzheimer’s disease 5–7 years before the onset of symptoms. Despite repeated setbacks of anti-dementia drugs in clinical trials across the world, he is convinced that a treatment will be found. Not only has he presided over 17 clinical trials in China but is also involved in 12 international clinical trials as China’s leading principal investigator in this field, highlighting his continuous efforts in the search for effective drugs for dementia.

Prof. Jia is universally recognized as the chief architect of Alzheimer’s disease research in China. He has served as the Founding Chair of the Neurologists Society of the Chinese Medical Doctor Association and as the Director of the Cognitive Disorders Committee. He has also served as the Founding President of the Neurology branch of the Chinese Medical Association and as the leader of the Dementia and Cognitive Impairment group. He has also been serving as the Founding Chair of the Dementia and Cognitive Disorders Working Committee of the Chinese Medical Doctor Association. Through his work in these organizations, he has addressed the challenges of an aging population in China. His most important contribution is the continuous development of 28 guidelines for the diagnosis and treatment of dementia, including the translation of the proposed criteria for Alzheimer’s disease dementia from the National Institute on Aging/Alzheimer’s Association into Chinese and its popularization in China. These efforts have increased the diagnosis rate by four times. He has also established a dementia specialist system and trained specialists for the benefit of 15 million patients with dementia and more than 30 million patients with mild cognitive impairment in China. Prof. Jia is leading and standardizing the field of dementia in China. He is an Advisory Editorial Board member of the journal “Alzheimer’s & Dementia” and an Editorial Board member of the journal “Alzheimer’s Research & Therapy.” He has authored over 960 publications with a total of 18200 citations, including more than 300 SCI papers. He has been selected as highly cited scholars in the world. He is the editor in chief of a series of neurology text book including Neurology (6th edition, 7th edition and 8th edition), widely used by 168 universities in China. Professor Jia won the second prize of national science and Technology Progress Award in 2013 and the first prize of Beijing Science and Technology Progress Award in 2020. In 2021, he won the Zaven Khachaturian scientific achievement award of the international Alzheimer’s Association. He is the first Chinese scholar to win this award.“As a leader in the field of dementia in China, Prof. Jia pioneered the genetic research of Alzheimer’s disease, reported important epidemiological data of dementia in China, standardized the diagnosis and treatment criteria for dementia, advocated and trained a large number of dementia professionals, and established memory clinics for patients with dementia to get timely and appropriate diagnosis and treatment. His work has improved the diagnosis and treatment quality of dementia in China, which accounts for one fifth of the world’s population, and has made outstanding contributions to the fight against dementia in China and even the world,” said Maria C. Carrillo, Ph.D., Chief Science Officer, Alzheimer’s Association.


  1. Jia J#*, Zhao T#, Liu Z, Liang Y, Li F, Li Y, Liu W, Li F, Shi S, Zhou C, Yang H, Liao Z, Li Y, Zhao H, Zhang J, Zhang K, Kan M, Yang S, Li H, Liu Z, Ma R, Lv J, Wang Y, Yan X, Liang F, Yuan X, Zhang J, Gauthier S, Cummings J. Association between healthy lifestyle and memory decline in older adults: 10 year, population based, prospective cohort study. BMJ. 2023 Jan 25;380:e072691.
  2. Jia J, Zhang Y, Shi Y, Yin X, Wang S, Li Y, Zhao T, Liu W, Zhou A, Jia L. A 19-Year-Old Adolescent with Probable Alzheimer’s Disease. J Alzheimers Dis. 2023;91(3):915-922.
  3. Jia J#*, Ning Y, Chen M, Wang S, Li Y, Yang H. Ending age discrimination and stigma to promote healthy ageing in China. Lancet (London, England). 2022;400(10367):1907-9.
  4. Liu W#, Gauthier S, Jia J*, Alzheimer’s disease: current status and perspective,  Science Bulletin, 2022;67(24):2494-2497.
  5. Xu L#, Li B#, Li F, Li Y, Qin W, Zhao Y, Jia J*. NMDA Receptor GluN2B Subunit Is Involved in Excitotoxicity Mediated by Death-Associated Protein Kinase 1 in Alzheimer’s Disease. J Alzheimers Dis. 2022.
  6. Wang Z#, Yang J, Zhu W, Tang Y*, Jia J. The synaptic marker neurogranin as a disease state biomarker in Alzheimer’s disease: a systematic review and meta-analysis. Int J Neurosci. 2022;132(12):1245-53.
  7. Wang C#, Wang Z#, Xie B, Shi X, Yang P, Liu L, Qu T, Qin Q, Xing Y, Zhu W, Teipel SJ, Jia J, Zhao G*, Li L*, Tang Y*. Binaural processing deficit and cognitive impairment in Alzheimer’s disease. Alzheimers Dement. 2022;18(6):1085-99.
  8. Song Y#, Quan M, Li T, Jia J*. Serum Homocysteine, Vitamin B12, Folate, and Their Association with Mild Cognitive Impairment and Subtypes of Dementia. J Alzheimers Dis. 2022;90(2):681-91.
  9. Qin W#, Li F, Jia L, Wang Q, Li Y, Wei Y, Li Y, Jin H, Jia J*. Phosphorylated Tau 181 Serum Levels Predict Alzheimer’s Disease in the Preclinical Stage. Front Aging Neurosci. 2022;14:900773.
  10. Mei F#, Hu J, Wu Z, Zhang G, Liu A, Li X, Zhu M, Gan Y, Liang L, Zhao X, Yuan Y, Meng X, Li Y, Jin Y, Jia J*, Yin Y*. FAM69C, a kinase critical for synaptic function and memory, is defective in neurodegenerative dementia. Cell reports. 2022;40(3):111101.
  11. Lyu D#, Jia J*. Cryptotanshinone Attenuates Amyloid-beta(42)-induced Tau Phosphorylation by Regulating PI3K/Akt/GSK3beta Pathway in HT22 Cells. Mol Neurobiol. 2022;59(7):4488-500.
  12. Liu W#, Li Y, Li Y, Xu L, Jia J*. Carnosic Acid Attenuates AbetaOs-Induced Apoptosis and Synaptic Impairment via Regulating NMDAR2B and Its Downstream Cascades in SH-SY5Y Cells. Mol Neurobiol. 2022.
  13. Li Y#, Qiao Y, Wang F, Wei C, Wang R, Jin H, Xie B, You J, Jia J, Zhou A*. Culture Effects on the Chinese Version Boston Naming Test Performance and the Normative Data in the Native Chinese-Speaking Elders in Mainland China. Front Neurol. 2022;13:866261.
  14. Gong M#, Jia J*. Contribution of blood-brain barrier-related blood-borne factors for Alzheimer’s disease vs. vascular dementia diagnosis: A pilot study. Frontiers in neuroscience. 2022;16:949129.
  15. Zhang H#, Lyu D#, Jia J*, Alzheimer’s Disease Neuroimaging I. The Trajectory of Cerebrospinal Fluid Growth-Associated Protein 43 in the Alzheimer’s Disease Continuum: A Longitudinal Study. J Alzheimers Dis. 2022;85(4):1441-52.
  16. Xing Y#, Yang J, Zhou A, Wang F, Tang Y*, Jia J*. Altered brain activity mediates the relationship between white matter hyperintensity severity and cognition in older adults. Brain Imaging Behav. 2022;16(2):899-908.
  17. Wei C#*, Lu X, Zou Q, Gong S, Chen Y, Lyu J, Jia J. Generation and characterization of a human induced pluripotent stem cell line (XWHNi001-A) derived from an Alzheimer’s disease patient with mutation in the APP gene. Stem cell research. 2022;60:102690.
  18. Wang Z#, Zhu W, Xing Y, Jia J, Tang Y*. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis. Nutr Rev. 2022;80(4):931-49.
  19. Wang Y#, Han X, Zhang X, Zhang Z, Cong L, Tang S, Hou T, Liu C, Han X, Zhang Q, Feng J, Yin L, Song L, Dong Y, Liu R, Li Y, Ngandu T, Kivipelto M, Snyder H, Carrillo M, Persson J, Fratiglioni L, Launer LJ, Jia J, Du Y*, Qiu C*. Health status and risk profiles for brain aging of rural-dwelling older adults: Data from the interdisciplinary baseline assessments in MIND-China. Alzheimers Dement (N Y). 2022;8(1):e12254.
  20. Wang F#*, Zhou A, Wei C, Zuo X, Ma X, Zhao L, Jin H, Li Y, Guo D, Jia J*. Good Performance of the Chinese Version of Mini Social Cognition and Emotional Assessment in the Early Diagnosis of Behavioral Variant Frontotemporal Dementia. Front Neurol. 2022;13:827945.
  21. Li B, Xu L, Li F, Li Y, Zhao Y, Zhang H, Quan M, Jia J*. CaMKIIalpha Signaling Is Required for the Neuroprotective Effects of Dl-3-n-Butylphthalide in Alzheimer’s Disease. Mol Neurobiol. 2022.
  22. Kong C#, Jia L, Jia J*. gamma-mangostin attenuates amyloid-beta42-induced neuroinflammation and oxidative stress in microglia-like BV2 cells via the mitogen-activated protein kinases signaling pathway. Eur J Pharmacol. 2022;917:174744.
  23. Jiao H#, Jia J*. Ginsenoside compound K acts via LRP1 to alleviate Amyloid beta42-induced neuroinflammation in microglia by suppressing NF-kappaB. Biochem Biophys Res Commun. 2022;590:14-19.
  24. Jia J#*, Li T#, Yang J#, Chen B, Qin W, Wei C, Song Y, Wang Q, Li Y, Jia L. Detection of plasma Aβ seeding activity by a newly developed analyzer for diagnosis of Alzheimer’s disease. Alzheimers Res Ther. 2022;14(1):21.
  25. Zhu M#, Jia L*, Jia J*. Inhibition of miR-96-5p May Reduce Aβ 42/Aβ40 Ratio via Regulating ATP-Binding Cassette A1. J Alzheimers Dis. 2021;83(1):367-377.
  26. Zhou Y#, Wang Y, Quan M, Zhao H, Jia J*. Gut Microbiota Changes and Their Correlation with Cognitive and Neuropsychiatric Symptoms in Alzheimer’s Disease. J Alzheimers Dis. 2021;81(2):583-595.
  27. Zhang H#, Wang Y#, Lyu D, Li Y, Li W, Wang Q, Li Y, Qin Q, Wang X, Gong M, Jiao H, Liu W, Jia J*. Cerebral blood flow in mild cognitive impairment and Alzheimer’s disease: A systematic review and meta-analysis. Ageing Res Rev. 2021;71:101450.
  28. Yang J#, Kong C, Jia L, Li T, Quan M, Li Y, Lyu D, Li F, Jin H, Li Y, Wang Q, Jia J*. Association of accelerated long-term forgetting and senescence-related blood-borne factors in asymptomatic individuals from families with autosomal dominant Alzheimer’s disease. Alzheimers Res Ther. 2021;13(1):107.
  29. Yang J#, Jia L*, Li Y, Qiu Q, Quan M, Jia J*. Fluid Biomarkers in Clinical Trials for Alzheimer’s Disease: Current and Future Application. J Alzheimers Dis. 2021;81(1):19-32.
  30. Xu L#, Li F#, Li B#, Cao S, Li Y, Xu J, Jia J*. Decreased Levels of Insulin-Like Growth Factor-1 Are Associated with Alzheimer’s Disease: A Meta-Analysis. J Alzheimers Dis. 2021;82(3):1357-1367.
  31. Xu H#, Jia J*. Single-Cell RNA Sequencing of Peripheral Blood Reveals Immune Cell Signatures in Alzheimer’s Disease. Front Immunol. 2021;12:645666.
  32. Xing Y#, Yang J, Zhou A, Wang F, Wei C, Tang Y*, Jia J*. White Matter Fractional Anisotropy Is a Superior Predictor for Cognitive Impairment Than Brain Volumes in Older Adults With Confluent White Matter Hyperintensities. Front Psychiatry. 2021;12:633811.
  33. Xing Y#, Yang J, Zhou A, Wang F, Tang Y*, Jia J*. Altered brain activity mediates the relationship between white matter hyperintensity severity and cognition in older adults. Brain Imaging Behav. 2021.
  34. Wang Z#, Zhu W, Xing Y, Jia J, Tang Y*. B vitamins and prevention of cognitive decline and incident dementia: a systematic review and meta-analysis. Nutr Rev. 2021.
  35. Wang Z#, Yang J, Zhu W, Tang Y*, Jia J. The synaptic marker neurogranin as a disease state biomarker in Alzheimer’s disease: a systematic review and meta-analysis. Int J Neurosci. 2021:1-9.
  36. Wang J#, Qiu Z, Li D, Yang X, Ding Y, Gao L, Liu A, Song Y, Li C, Gao R, Wang L, Wu L, Jia L, Guo D, Zhou A, Jia J, Huang L, Qu M, Gao L, Dong H, Hao J*, Liu Z*. Clinical and Imaging Features of Patients With Encephalitic Symptoms and Myelin Oligodendrocyte Glycoprotein Antibodies. Front Immunol. 2021;12:722404.
  37. Wang F#, Ma X#, Shi Y, Jia L, Zuo X, Yu Y, Jin H, Tang Y, Guo D, Jia J*. Cognitive profiles in adult-onset neuronal intranuclear inclusion disease: a case series from the memory clinic. Neurol Sci. 2021;42(6):2487-2495.
  38. Wang C#, Wang Z, Xie B, Shi X, Yang P, Liu L, Qu T, Qin Q, Xing Y, Zhu W, Teipel SJ, Jia J, Zhao G*, Li L*, Tang Y*. Binaural processing deficit and cognitive impairment in Alzheimer’s disease. Alzheimers Dement. 2021.
  39. Qin W#, Zhou A, Zuo X, Jia L, Li F, Wang Q, Li Y, Wei Y, Jin H, Cruchaga C, Benitez BA, Jia J*. Exome sequencing revealed PDE11A as a novel candidate gene for early-onset Alzheimer’s disease. Hum Mol Genet. 2021;30(9):811-822.
  40. Qin W#, Li W#, Wang Q, Gong M, Li T, Shi Y, Song Y, Li Y, Li F, Jia J*. Race-Related Association between APOE Genotype and Alzheimer’s Disease: A Systematic Review and Meta-Analysis. J Alzheimers Dis. 2021;83(2):897-906.
  41. Qin Q#, Wei C*, Piao Y, Lian F, Wu H, Zhou A, Wang F, Zuo X, Han Y, Lyu J, Guo D, Jia J. Current Review of Leptomeningeal Amyloidosis Associated With Transthyretin Mutations. Neurologist. 2021;26(5):189-195.
  42. Qin Q#, Tang Y*, Dou X, Qu Y, Xing Y, Yang J, Chu T, Liu Y, Jia J. Default mode network integrity changes contribute to cognitive deficits in subcortical vascular cognitive impairment, no dementia. Brain Imaging Behav. 2021;15(1):255-265.
  43. Li W#, Wang S, Zhang H, Li B, Xu L, Li Y, Kong C, Jiao H, Wang Y, Pang Y, Qin W, Jia L, Jia J*. Honokiol Restores Microglial Phagocytosis by Reversing Metabolic Reprogramming. J Alzheimers Dis. 2021;82(4):1475-1485.
  44. Li F#, Qin W, Zhu M, Jia J*. Model-Based Projection of Dementia Prevalence in China and Worldwide: 2020-2050. J Alzheimers Dis. 2021;82(4):1823-1831.
  45. Kandiah N#*, Chan YF, Chen C, Dasig D, Dominguez J, Han SH, Jia J, Kim S, Limpawattana P, Ng LL, Nguyen DT, Ong PA, Raya-Ampil E, Saedon N, Senanarong V, Setiati S, Singh H, Suthisisang C, Trang TM, Turana Y, Venketasubramanian N, Yong FM, Youn YC, Ihl R. Strategies for the use of Ginkgo biloba extract, EGb 761((R)) , in the treatment and management of mild cognitive impairment in Asia: Expert consensus. CNS Neurosci Ther. 2021;27(2):149-162.
  46. Jia L#, Zhu M, Kong C, Pang Y, Zhang H, Qiu Q, Wei C, Tang Y, Wang Q, Li Y, Li T, Li F, Wang Q, Li Y, Wei Y, Jia J*. Blood neuro-exosomal synaptic proteins predict Alzheimer’s disease at the asymptomatic stage. Alzheimers Dement. 2021;17(1):49-60.
  47. Jia L#, Li F, Wei C, Zhu M, Qu Q, Qin W, Tang Y, Shen L, Wang Y, Shen L, Li H, Peng D, Tan L, Luo B, Guo Q, Tang M, Du Y, Zhang J, Zhang J, Lyu J, Li Y, Zhou A, Wang F, Chu C, Song H, Wu L, Zuo X, Han Y, Liang J, Wang Q, Jin H, Wang W, Lu Y, Li F, Zhou Y, Zhang W, Liao Z, Qiu Q, Li Y, Kong C, Li Y, Jiao H, Lu J*, Jia J*. Prediction of Alzheimer’s disease using multi-variants from a Chinese genome-wide association study. Brain. 2021;144(3):924-937.
  48. Hao J#, Qiao Y, Li T, Yang J, Song Y, Jia L, Jia J*. Investigating Changes in the Serum Inflammatory Factors in Alzheimer’s Disease and Their Correlation with Cognitive Function. J Alzheimers Dis. 2021;84(2):835-842.
  49. Hampel H#*, Shaw LM, Aisen P, Chen C, Lleó A, Iwatsubo T, Iwata A, Yamada M, Ikeuchi T, Jia J, Wang H, Teunissen CE, Peskind E, Blennow K, Cummings J, Vergallo A. State-of-the-art of lumbar puncture and its place in the journey of patients with Alzheimer’s disease. Alzheimers Dement. 2021.
  50. Fu Y#, Jia J*. Isoliquiritigenin Confers Neuroprotection and Alleviates Amyloid-beta42-Induced Neuroinflammation in Microglia by Regulating the Nrf2/NF-kappaB Signaling. Front Neurosci. 2021;15:638772.
  51. Chen C#, Zhou Y, Wang H, Alam A, Kang SS, Ahn EH, Liu X, Jia J, Ye K*. Gut inflammation triggers C/EBPβ/δ-secretase-dependent gut-to-brain propagation of Aβ and Tau fibrils in Alzheimer’s disease. EMBO J. 2021;40(17):e106320.
  52. Zhu M#, Jia L, Li F, Jia J*. Identification of KIAA0513 and Other Hub Genes Associated With Alzheimer Disease Using Weighted Gene Coexpression Network Analysis. Front Genet. 2020;11:981.
  53. Zhao T#, Quan M#, Jia J*. Functional Connectivity of Default Mode Network Subsystems in the Presymptomatic Stage of Autosomal Dominant Alzheimer’s Disease. J Alzheimers Dis. 2020;73(4):1435-1444.
  54. Zhang H#, Jia L, Jia J*. Oxiracetam Offers Neuroprotection by Reducing Amyloid beta-Induced Microglial Activation and Inflammation in Alzheimer’s Disease. Front Neurol. 2020;11:623.
  55. Yu J#*, Xu W#, Tan C#, Andrieu S, Suckling J, Evangelou E, Pan A, Zhang C, Jia J, Feng L, Kua EH, Wang YJ, Wang HF, Tan MS, Li JQ, Hou XH, Wan Y, Tan L, Mok V, Tan L, Dong Q, Touchon J, Gauthier S, Aisen PS, Vellas B. Evidence-based prevention of Alzheimer’s disease: systematic review and meta-analysis of 243 observational prospective studies and 153 randomised controlled trials. J Neurol Neurosurg Psychiatry. 2020;91(11):1201-1209.
  56. Yang H#, Wang W, Jia L, Qin W, Hou T, Wu Q, Li H, Tian Y, Jia J*. The Effect of Chronic Cerebral Hypoperfusion on Blood-Brain Barrier Permeability in a Transgenic Alzheimer’s Disease Mouse Model (PS1V97L). J Alzheimers Dis. 2020;74(1):261-275.
  57. Xu H#, Jia J*. Immune-Related Hub Genes and the Competitive Endogenous RNA Network in Alzheimer’s Disease. J Alzheimers Dis. 2020;77(3):1255-1265.
  58. Xing Y#, Zhu Z, Du Y, Zhang J, Qu Q, Sun L, Li Y, Guo Y, Peng G, Liu Y, Yu Y, Qiao Y, Xie B, Shi X, Lu J, Jia J, Tang Y*. The Efficacy of COGnitive tRaining in patiEnts with Amnestic mild coGnitive impairmENT (COG-REAGENT): Protocol for a Multi-Center Randomized Controlled Trial. J Alzheimers Dis. 2020;75(3):779-787.
  59. Xing Y#, Wei P, Wang C, Shan Y, Yu Y, Qiao Y, Xie B, Shi X, Zhu Z, Lu J, Zhao G, Jia J, Tang Y*. TRanscranial AlterNating current Stimulation FOR patients with Mild Alzheimer’s Disease (TRANSFORM-AD study): Protocol for a randomized controlled clinical trial. Alzheimers Dement (N Y). 2020;6(1):e12005.
  60. Wang W#, Wei C, Quan M, Li T, Jia J*. Sulforaphane Reverses the Amyloid-β Oligomers Induced Depressive-Like Behavior. J Alzheimers Dis. 2020;78(1):127-137.
  61. Shiells H#, Schelter BO, Bentham P, Baddeley TC, Rubino CM, Ganesan H, Hammel J, Vuksanovic V, Staff RT, Murray AD, Bracoud L, Wischik DJ, Riedel G, Gauthier S, Jia J, Moebius HJ, Hardlund J, Kipps CM, Kook K, Storey JMD, Harrington CR, Wischik CM*. Concentration-Dependent Activity of Hydromethylthionine on Clinical Decline and Brain Atrophy in a Randomized Controlled Trial in Behavioral Variant Frontotemporal Dementia. J Alzheimers Dis. 2020;75(2):501-519.
  62. Quan M#, Zhao T, Tang Y, Luo P, Wang W, Qin Q, Li T, Wang Q, Fang J, Jia J*. Effects of gene mutation and disease progression on representative neural circuits in familial Alzheimer’s disease. Alzheimers Res Ther. 2020;12(1):14.
  63. Qiu Q#, Jia L, Wang Q, Zhao L, Jin H, Li T, Quan M, Xu L, Li B, Li Y, Jia J*. Identification of a novel PSEN1 Gly111Val missense mutation in a Chinese pedigree with early-onset Alzheimer’s disease. Neurobiol Aging. 2020;85:155.e151-155.e154.
  64. Qin Q#, Yin Y, Wang Y, Lu Y, Tang Y*, Jia J*. Gene mutations associated with early onset familial Alzheimer’s disease in China: An overview and current status. Mol Genet Genomic Med. 2020:e1443.
  65. Mok VCT#*, Pendlebury S, Wong A, Alladi S, Au L, Bath PM, Biessels GJ, Chen C, Cordonnier C, Dichgans M, Dominguez J, Gorelick PB, Kim S, Kwok T, Greenberg SM, Jia J, Kalaria R, Kivipelto M, Naegandran K, Lam LCW, Lam BYK, Lee ATC, Markus HS, O’Brien J, Pai MC, Pantoni L, Sachdev P, Skoog I, Smith EE, Srikanth V, Suh GH, Wardlaw J, Ko H, Black SE, Scheltens P. Tackling challenges in care of Alzheimer’s disease and other dementias amid the COVID-19 pandemic, now and in the future. Alzheimers Dement. 2020.
  66. Jia L#, Xu H, Chen S, Wang X, Yang J, Gong M, Wei C, Tang Y, Qu Q, Chu L, Shen L, Zhou C, Wang Q, Zhao T, Zhou A, Li Y, Li F, Li Y, Jin H, Qin Q, Jiao H, Li Y, Zhang H, Lyu D, Shi Y, Song Y, Jia J*. The APOE epsilon4 exerts differential effects on familial and other subtypes of Alzheimer’s disease. Alzheimers Dement. 2020;16(12):1613-1623.
  67. Jia L#, Quan M, Fu Y, Zhao T, Li Y, Wei C, Tang Y, Qin Q, Wang F, Qiao Y, Shi S, Wang Y, Du Y, Zhang J, Zhang J, Luo B, Qu Q, Zhou C, Gauthier S, Jia J*, Group for the Project of Dementia Situation in C. Dementia in China: epidemiology, clinical management, and research advances. Lancet Neurol. 2020;19(1):81-92.
  68. Jia L#, Fu Y, Shen L, Zhang H, Zhu M, Qiu Q, Wang Q, Yan X, Kong C, Hao J, Wei C, Tang Y, Qin W, Li Y, Wang F, Guo D, Zhou A, Zuo X, Yu Y, Li D, Zhao L, Jin H, Jia J*. PSEN1, PSEN2, and APP mutations in 404 Chinese pedigrees with familial Alzheimer’s disease. Alzheimers Dement. 2020;16(1):178-191.
  69. Jia L#, Du Y, Chu L, Zhang Z, Li F, Lyu D, Li Y, Li Y, Zhu M, Jiao H, Song Y, Shi Y, Zhang H, Gong M, Wei C, Tang Y, Fang B, Guo D, Wang F, Zhou A, Chu C, Zuo X, Yu Y, Yuan Q, Wang W, Li F, Shi S, Yang H, Zhou C, Liao Z, Lv Y, Li Y, Kan M, Zhao H, Wang S, Yang S, Li H, Liu Z, Wang Q, Qin W, Jia J*, Quan M, Wang Y, Li W, Cao S, Xu L, Han Y, Liang J, Qiao Y, Qin Q, Qiu Q. Prevalence, risk factors, and management of dementia and mild cognitive impairment in adults aged 60 years or older in China: a cross-sectional study. The Lancet Public Health. 2020;5(12):e661-e671.
  70. Jia J#*, Wei C, Chen W, Jia L, Zhou A, Wang F, Tang Y, Xu L. Safety and Efficacy of Donepezil 10 mg/day in Patients with Mild to Moderate Alzheimer’s Disease. J Alzheimers Dis. 2020;74(1):199-211.
  71. Jia J#*. Response to letter to the editor. J Neurol Sci. 2020;417:116966.
  72. Han Y#, Zhou A, Li F, Wang Q, Xu L, Jia J*. Apolipoprotein E ε4 allele is associated with vascular cognitive impairment no dementia in Chinese population. J Neurol Sci. 2020;409:116606.
  73. Fan C#, Huang X#, Song H, Jia J*. Presenilin 1 intronic polymorphism in sporadic Alzheimer’s disease in a Northern Chinese population. Neuroreport. 2020;31(1):37-40.
  74. Chen S#, Jia J*. Tenuifolin Attenuates Amyloid-β42-Induced Neuroinflammation in Microglia Through the NF-κB Signaling Pathway. J Alzheimers Dis. 2020;76(1):195-205.
  75. Zhang J#, Yue X#, Luo H, Jiang W, Mei Y, Ai L, Gao G, Wu Y, Yang H, An J, Ding S, Yang X, Sun B, Luo W*, He R*, Jia J*, Lyu J*, Tong Z*. Illumination with 630 nm Red Light Reduces Oxidative Stress and Restores Memory by Photo-Activating Catalase and Formaldehyde Dehydrogenase in SAMP8 Mice. Antioxid Redox Signal. 2019;30(11):1432-1449.
  76. Zhang J#, Chen B#, Lu J, Wu Y, Wang S, Yao Z, Zhu L, Qiao Y, Sun Q, Qin W, Zhao Q, Jia J, Wei C*. Brains of rhesus monkeys display Aβ deposits and glial pathology while lacking Aβ dimers and other Alzheimer’s pathologies. Aging Cell. 2019;18(4):e12978.
  77. Yan X#, Li F#, Chen S, Jia J*. Associated Factors of Total Costs of Alzheimer’s Disease: A Cluster-Randomized Observational Study in China. J Alzheimers Dis. 2019;69(3):795-806.
  78. Xu L#, Li B, Jia J*. DAPK1: a Novel Pathology and Treatment Target for Alzheimer’s Disease. Mol Neurobiol. 2019;56(4):2838-2844.
  79. Wu S#, Wu B#, Liu M*, Chen Z, Wang W, Anderson CS, Sandercock P, Wang Y, Huang Y, Cui L, Pu C, Jia J, Zhang T, Liu X, Zhang S, Xie P, Fan D, Ji X, Wong KL, Wang L, China Stroke Study C. Stroke in China: advances and challenges in epidemiology, prevention, and management. Lancet Neurol. 2019;18(4):394-405.
  80. Wei C#*, Qin Q#, Chen F, Zhou A, Wang F, Zuo X, Chen R, Lyu J, Jia J. Adult-onset vanishing white matter disease with the EIF2B2 gene mutation presenting as menometrorrhagia. BMC Neurol. 2019;19(1):203.
  81. Wang W#, Hou T, Jia L, Wu Q, Quan M, Jia J*. Toxic amyloid-beta oligomers induced self-replication in astrocytes triggering neuronal injury. EBioMedicine. 2019;42:174-187.
  82. Tian Y#, Wang W, Xu L, Li H, Wei Y, Wu Q, Jia J*. Activation of Nrf2/ARE pathway alleviates the cognitive deficits in PS1V97L-Tg mouse model of Alzheimer’s disease through modulation of oxidative stress. J Neurosci Res. 2019;97(4):492-505.
  83. Tang Y#*, Xing Y#, Zhu Z, He Y, Li F, Yang J, Liu Q, Li F, Teipel SJ, Zhao G*, Jia J*. The effects of 7-week cognitive training in patients with vascular cognitive impairment, no dementia (the Cog-VACCINE study): A randomized controlled trial. Alzheimers Dement. 2019;15(5):605-614.
  84. Tang Y#*, Qin Q*, Xing Y, Guo D, Di L, Jia J. AARS2 leukoencephalopathy: A new variant of mitochondrial encephalomyopathy. Mol Genet Genomic Med. 2019;7(4):e00582.
  85. Shen L#, Qin W, Wu L, Zhou A, Tang Y, Wang Q, Jia L, Jia J*. Two novel presenilin-1 mutations (I249L and P433S) in early onset Chinese Alzheimer’s pedigrees and their functional characterization. Biochem Biophys Res Commun. 2019;516(1):264-269.
  86. Schelter BO#, Shiells H, Baddeley TC, Rubino CM, Ganesan H, Hammel J, Vuksanovic V, Staff RT, Murray AD, Bracoud L, Riedel G, Gauthier S, Jia J, Bentham P, Kook K, Storey JMD, Harrington CR, Wischik CM*. Concentration-Dependent Activity of Hydromethylthionine on Cognitive Decline and Brain Atrophy in Mild to Moderate Alzheimer’s Disease. J Alzheimers Dis. 2019;72(3):931-946.
  87. Qiu Q#, Shen L, Jia L, Wang Q, Li F, Li Y, Jia J*. A Novel PSEN1 M139L Mutation Found in a Chinese Pedigree with Early-Onset Alzheimer’s Disease Increases Aβ42/Aβ40 ratio. J Alzheimers Dis. 2019;69(1):199-212.
  88. Liu J#, Wang Q#, Jing D, Gao R, Zhang J, Cui C, Qiao H, Liang Z, Wang C, Rosa-Neto P, Wu L*, Jia J, Gauthier S. Diagnostic Approach of Early-Onset Dementia with Negative Family History: Implications from Two Cases of Early-Onset Alzheimer’s Disease with De Novo PSEN1 Mutation. J Alzheimers Dis. 2019;68(2):551-558.
  89. Jia L#, Qiu Q, Zhang H, Chu L, Du Y, Zhang J, Zhou C, Liang F, Shi S, Wang S, Qin W, Wang Q, Li F, Wang Q, Li Y, Shen L, Wei Y, Jia J*. Concordance between the assessment of Abeta42, T-tau, and P-T181-tau in peripheral blood neuronal-derived exosomes and cerebrospinal fluid. Alzheimers Dement. 2019;15(8):1071-1080.
  90. Jia J#*, Ji Y, Feng T, Ye Q, Peng D, Kuang W, Ning Y, Liang Z, Fan D, Wei W, Li Y, Xiao S. Sixteen-Week Interventional Study to Evaluate the Clinical Effects and Safety of Rivastigmine Capsules in Chinese Patients with Alzheimer’s Disease. J Alzheimers Dis. 2019;72(4):1313-1322.
  91. Fu X#, Chu C, Li X, Gao Q, Jia J*. Cerebral arterial stiffness for predicting functional outcome in acute ischemic stroke. Hypertens Res. 2019;42(12):1916-1922.
  92. Cao B#, Cao J, Ding L, Gao L, Guo T, Huang X, Jiang W, Li H, Li L, Lu G, Ma J, Niu X, Pan S, Peng B, Qian S, Su Y*, Tan G, Teng J, Tian F, Wang H, Wang C, Wang F, Wang N, Xu P, Xu Y, Yuan J, Zeng L, Zhang L, Zhang M, Zhang X, Zhang X, Zhao G*, Zhou D, Chen W, Deng W, Du R, Fan L, Hu Y, Jiang Y, Min M, Li W, Li X, Li Y, Liu G, Liu J, Liu Y, Lu C, Ma J, Ma L, Ming M, Shao H, Sun H, Tang N, Tian F, Tian L, Wang H, Wang L, Wang Q, Wang S, Wang Y, Xing Q, Ye H, Ye H, Zhang L, Zhang L, Zhang Y, Zhang Z, Zhang X, Zhou B, Zhou S, Zhou Y, Zhu W, Chen Y, Cui L, Du B, Jia J, Ling F, Liu J, Pu C, Shen K, Xi X, Xiong L, Yu X, Zhao Z, Zhao J, Wang Y. Criteria and practical guidance for determination of brain death in adults (2nd edition). Chin Med J (Engl). 2019;132(3):329-335.
  93. Yang H#, Hou T#, Wang W, Luo Y, Yan F, Jia J*. The Effect of Chronic Cerebral Hypoperfusion on Amyloid-β Metabolism in a Transgenic Mouse Model of Alzheimer’s Disease (PS1V97L). J Alzheimers Dis. 2018;62(4):1609-1621.
  94. Wu L#, Zhan S, Huang Z, Zhang B, Wang T, Liu C, Lu H, Dong X, Wu Z, Zhang J, Zhang J, Zhao Z, Han F, Huang Y, Lu J, Gauthier S, Jia J, Wang Y*. Expert Consensus on Clinical Diagnostic Criteria for Fatal Familial Insomnia. Chin Med J (Engl). 2018;131(13):1613-1617.
  95. Wu L#*, Liu J#, Feng X, Dong J, Qin W, Liu Y, Wang J, Lu J, Chen K, Wang Y, Jia J. 11C-CFT-PET in Presymptomatic FTDP-17: A Potential Biomarker Predicting Onset. J Alzheimers Dis. 2018;61(2):613-618.
  96. Wilcock GK#, Gauthier S, Frisoni GB, Jia J, Hardlund JH, Moebius HJ, Bentham P, Kook KA, Schelter BO, Wischik DJ, Davis CS, Staff RT, Vuksanovic V, Ahearn T, Bracoud L, Shamsi K, Marek K, Seibyl J, Riedel G, Storey JMD, Harrington CR, Wischik CM*. Potential of Low Dose Leuco-Methylthioninium Bis(Hydromethanesulphonate) (LMTM) Monotherapy for Treatment of Mild Alzheimer’s Disease: Cohort Analysis as Modified Primary Outcome in a Phase III Clinical Trial. J Alzheimers Dis. 2018;61(1):435-457.
  97. Wang Z#, Gong K#, Liu X, Zhang Z, Sun X, Wei Z, Yu S, Manfredsson F, Sandoval IM, Johnson PF, Jia J*, Wang J*, Ye K*. C/EBPβ regulates delta-secretase expression and mediates pathogenesis in mouse models of Alzheimer’s disease. Nat Commun. 2018;9(1):1784.
  98. Wang Z#, Qin W, Wei C, Tang Y, Zhao L, Jin H, Li Y, Wang Q, Luan X, He J, Jia J*. The microRNA-1908 up-regulation in the peripheral blood cells impairs amyloid clearance by targeting ApoE. Int J Geriatr Psychiatry. 2018;33(7):980-986.
  99. Wang F#, Guo D, Liu Z, Zhou A, Wei C, Jia J*. Neurosarcoidosis: clinical characteristics, diagnosis, and treatment in eight Chinese patients. Neurol Sci. 2018;39(10):1725-1733.
  100. Li J#, Wu L, Tang Y, Zhou A, Wang F, Xing Y, Jia J*. Differentiation of neuropsychological features between posterior cortical atrophy and early onset Alzheimer’s disease. BMC Neurol. 2018;18(1):65.
  101. Li H#, Jia J*, Wang W, Hou T, Tian Y, Wu Q, Xu L, Wei Y, Wang X. Honokiol Alleviates Cognitive Deficits of Alzheimer’s Disease (PS1V97L) Transgenic Mice by Activating Mitochondrial SIRT3. J Alzheimers Dis. 2018;64(1):291-302.
  102. Jia J#*, Wei C*, Chen S, Li F, Tang Y, Qin W, Zhao L, Jin H, Xu H, Wang F, Zhou A, Zuo X, Wu L, Han Y, Han Y, Huang L, Wang Q, Li D, Chu C, Shi L, Gong M, Du Y, Zhang J, Zhang J, Zhou C, Lv J, Lv Y, Xie H, Ji Y, Li F, Yu E, Luo B, Wang Y, Yang S, Qu Q, Guo Q, Liang F, Zhang J, Tan L, Shen L, Zhang K, Zhang J, Peng D, Tang M, Lv P, Fang B, Chu L, Jia L, Gauthier S*. The cost of Alzheimer’s disease in China and re-estimation of costs worldwide. Alzheimers Dement. 2018;14(4):483-491.
  103. Jia J#*, Wei C, Chen S, Li F, Tang Y, Qin W, Shi L, Gong M, Xu H, Li F, He J, Song H, Yang S, Zhou A, Wang F, Zuo X, Chu C, Liang J, Jia L, Gauthier S. Efficacy and safety of the compound Chinese medicine SaiLuoTong in vascular dementia: A randomized clinical trial. Alzheimers Dement (N Y). 2018;4:108-117.
  104. Hou T#, Yang H#, Wang W, Wu Q, Tian Y, Jia J*. Sulforaphane Inhibits the Generation of Amyloid-β Oligomer and Promotes Spatial Learning and Memory in Alzheimer’s Disease (PS1V97L) Transgenic Mice. J Alzheimers Dis. 2018;62(4):1803-1813.
  105. Feng X#, Zhou A#, Liu Z, Li F, Wei C, Zhang G, Jia J*. Validation of the Delayed Matching-to-Sample Task 48 (DMS48) in Elderly Chinese. J Alzheimers Dis. 2018;61(4):1611-1618.
  106. Zhang G#, Xie Y, Wang W, Feng X, Jia J*. Clinical characterization of an APP mutation (V717I) in five Han Chinese families with early-onset Alzheimer’s disease. J Neurol Sci. 2017;372:379-386.
  107. Wu L#*, An H, Liu J, Li J, Han Y, Zhou A, Wang F, Jia J. Manic-depressive Psychosis as the Initial Symptom in Adult Siblings with Late-onset Combined Methylmalonic Aciduria and Homocystinemia, Cobalamin C Type. Chin Med J (Engl). 2017;130(4):492-494.
  108. Wu L#, Lu H#, Wang X, Liu J, Huang C, Ye J, Li C, Lu J, Wang Y, Jia J, Zhan S*. Clinical Features and Sleep Analysis of Chinese Patients with Fatal Familial Insomnia. Sci Rep. 2017;7(1):3625.
  109. Wu L#, Liu J, Sha L, Wang X, Li J, Dong J, Jia J*. Sporadic Cases with Novel Mutations and Pedigree in Hereditary Leukoencephalopathy with Axonal Spheroids. J Alzheimers Dis. 2017;56(3):893-898.
  110. Tong Z#*, Wang W#, Luo W#, Lv J#, Li H#, Luo H, Jia J, He R*. Urine Formaldehyde Predicts Cognitive Impairment in Post-Stroke Dementia and Alzheimer’s Disease. J Alzheimers Dis. 2017;55(3):1031-1038.
  111. Liu Q#, Zhu Z#, Teipel SJ, Yang J, Xing Y, Tang Y*, Jia J*. White Matter Damage in the Cholinergic System Contributes to Cognitive Impairment in Subcortical Vascular Cognitive Impairment, No Dementia. Front Aging Neurosci. 2017;9:47.
  112. Liu D#, Li Z#, Zhang X, Zhao L, Jia J, Sun F, Wang Y, Ma D, Wei W*. Assessment of intracranial pressure with ultrasonographic retrobulbar optic nerve sheath diameter measurement. BMC Neurol. 2017;17(1):188.
  113. Li F#, Chen S#, Wei C*, Jia J*. Monetary costs of Alzheimer’s disease in China: protocol for a cluster-randomised observational study. BMC Neurol. 2017;17(1):15.
  114. Li D#, Hu N, Yu Y, Zhou A, Li F, Jia J*. Trajectories of Multidimensional Caregiver Burden in Chinese Informal Caregivers for Dementia: Evidence from Exploratory and Confirmatory Factor Analysis of the Zarit Burden Interview. J Alzheimers Dis. 2017;59(4):1317-1325.
  115. Jia J#*, Wei C*, Jia L, Tang Y, Liang J, Zhou A, Li F, Shi L, Doody RS*. Efficacy and Safety of Donepezil in Chinese Patients with Severe Alzheimer’s Disease: A Randomized Controlled Trial. J Alzheimers Dis. 2017;56(4):1495-1504.
  116. Jia J#*, Gauthier S*, Pallotta S, Ji Y, Wei W, Xiao S, Peng D, Guo Q, Wu L, Chen S, Kuang W, Zhang J, Wei C, Tang Y. Consensus-based recommendations for the management of rapid cognitive decline due to Alzheimer’s disease. Alzheimers Dement. 2017;13(5):592-597.
  117. Ikram MA#*, Bersano A, Manso-Calderón R, Jia J, Schmidt H, Middleton L, Nacmias B, Siddiqi S, Adams HH. Genetics of vascular dementia – review from the ICVD working group. BMC Med. 2017;15(1):48.
  118. Guo Y#*, Wang S, Jiang B, Li J, Liu L, Wang J, Zhao W, Jia J. Encephalitis with reversible splenial and deep cerebral white matter lesions associated with Epstein-Barr virus infection in adults. Neuropsychiatr Dis Treat. 2017;13:2085-2092.
  119. Gauthier S#*, Jia J, Belleville S, Cloutier S, Sadovnick D, Guimond C, Robb L, Masellis M, Rouleau G, Wu L, Rosa P. Perspectives on a collaborative Canada-China research program on diagnostic biomarkers for pre-dementia stages of Alzheimer’s Disease. Journal of Translational Neuroscience. 2017;2(3):1-6.
  120. Dong J#, Qin W, Wei C, Tang Y, Wang Q, Jia J*. A Novel PSEN1 K311R Mutation Discovered in Chinese Families with Late-Onset Alzheimer’s Disease Affects Amyloid-β Production and Tau Phosphorylation. J Alzheimers Dis. 2017;57(2):613-623.
  121. Yuan X#, Han Y, Wei Y, Xia M, Sheng C, Jia J*, He Y. Regional homogeneity changes in amnestic mild cognitive impairment patients. Neurosci Lett. 2016;629:1-8.
  122. Xing Y#, Tang Y#, Zhao L, Wang Q, Qin W, Zhang J*, Jia J*. Plasma Ceramides and Neuropsychiatric Symptoms of Alzheimer’s Disease. J Alzheimers Dis. 2016;52(3):1029-1035.
  123. Xing Y#, Tang Y#, Zhao L, Wang Q, Qin W, Ji X, Zhang J*, Jia J*. Associations between plasma ceramides and cognitive and neuropsychiatric manifestations in Parkinson’s disease dementia. J Neurol Sci. 2016;370:82-87.
  124. Wei C#, Jia J*, Wang F, Zhou A, Zuo X, Chu C. Overlap between Headache, Depression, and Anxiety in General Neurological Clinics: A Cross-sectional Study. Chin Med J (Engl). 2016;129(12):1394-1399.
  125. Wang W#, Lu L, Wu Q, Jia J*. Brain Amyloid-β Plays an Initiating Role in the Pathophysiological Process of the PS1V97L-Tg Mouse Model of Alzheimer’s Disease. J Alzheimers Dis. 2016;52(3):1089-1099.
  126. Wang H#, Tan L*, Cao L, Zhu X, Jiang T, Tan M, Liu Y, Wang C, Tsai RM, Jia J, Yu J*. Application of the IWG-2 Diagnostic Criteria for Alzheimer’s Disease to the ADNI. J Alzheimers Dis. 2016;51(1):227-236.
  127. Tang Y#*, Zhu Z#, Liu Q, Li F, Yang J, Li F, Xing Y, Jia J*. The efficacy of Cognitive training in patients with VAsCular Cognitive Impairment, No dEmentia (the Cog-VACCINE study): study protocol for a randomized controlled trial. Trials. 2016;17(1):392.
  128. Shen L#, Jia J*. An Overview of Genome-Wide Association Studies in Alzheimer’s Disease. Neurosci Bull. 2016;32(2):183-190.
  129. Mei Y#, Duan C#, Li X, Zhao Y, Cao F, Shang S, Ding S, Yue X, Gao G, Yang H, Shen L, Feng X, Jia J, Tong Z*, Yang X*. Reduction of Endogenous Melatonin Accelerates Cognitive Decline in Mice in a Simulated Occupational Formaldehyde Exposure Environment. Int J Environ Res Public Health. 2016;13(3).
  130. Ma Q#, Zhao H, Tao Z, Wang R, Liu P, Han Z, Ma S, Luo Y*, Jia J*. MicroRNA-181c Exacerbates Brain Injury in Acute Ischemic Stroke. Aging Dis. 2016;7(6):705-714.
  131. Li H#, Jia J*, Yang Z. Mini-Mental State Examination in Elderly Chinese: A Population-Based Normative Study. J Alzheimers Dis. 2016;53(2):487-496.
  132. Jia J#*, Zuo X, Jia X, Chu C, Wu L, Zhou A, Wei C, Tang Y, Li D, Qin W, Song H, Ma Q, Li J, Sun Y, Min B, Xue S, Xu E, Yuan Q, Wang M, Huang X, Fan C, Liu J, Ren Y, Jia Q, Wang Q, Jiao L, Xing Y, Wu X, China C, Aging Study G. Diagnosis and treatment of dementia in neurology outpatient departments of general hospitals in China. Alzheimers Dement. 2016;12(4):446-453.
  133. Jia J#*, Wei C, Liang J, Zhou A, Zuo X, Song H, Wu L, Chen X, Chen S, Zhang J, Wu J, Wang K, Chu L, Peng D, Lv P, Guo H, Niu X, Chen Y, Dong W, Han X, Fang B, Peng M, Li D, Jia Q, Huang L. The effects of DL-3-n-butylphthalide in patients with vascular cognitive impairment without dementia caused by subcortical ischemic small vessel disease: A multicentre, randomized, double-blind, placebo-controlled trial. Alzheimers Dement. 2016;12(2):89-99.
  134. Zou X#, Chung Y, Zhang L, Han Y, Yang Q, Jia J*. Middle Cerebral Artery Atherosclerotic Plaques in Recent Small Subcortical Infarction: A Three-Dimensional High-resolution MR Study. Biomed Res Int. 2015;2015:540217.
  135. Zhang Z#, Song M, Liu X, Su Kang S, Duong DM, Seyfried NT, Cao X, Cheng L, Sun Y*, Ping Yu S, Jia J*, Levey AI*, Ye K*. Delta-secretase cleaves amyloid precursor protein and regulates the pathogenesis in Alzheimer’s disease. Nat Commun. 2015;6:8762.
  136. Zhang Y#, Jin M, Du B, Lin H, Xu C, Jiang W, Jia J*. A Novel Canine Model of Acute Vertebral Artery Occlusion. PLoS One. 2015;10(11):e0142251.
  137. Xing Y#, Tang Y, Jia J*. Sex Differences in Neuropsychiatric Symptoms of Alzheimer’s Disease: The Modifying Effect of Apolipoprotein E ε4 Status. Behav Neurol. 2015;2015:275256.
  138. Xing Y#, Liu J#, Xu J, Yin L, Wang L, Li J, Yu Z, Li F, Gao R, Jia J*. Association between Plasma Leptin and Estrogen in Female Patients of Amnestic Mild Cognitive Impairment. Dis Markers. 2015;2015:450237.
  139. Xie Y#, Cui Z#, Zhang Z, Sun Y, Sheng C, Li K, Gong G*, Han Y*, Jia J*. Identification of Amnestic Mild Cognitive Impairment Using Multi-Modal Brain Features: A Combined Structural MRI and Diffusion Tensor Imaging Study. J Alzheimers Dis. 2015;47(2):509-522.
  140. Wang X#, Li C, Xing Y, Yang Y, Jia J*. Hypervalinemia and hyperleucine-isoleucinemia caused by mutations in the branched-chain-amino-acid aminotransferase gene. J Inherit Metab Dis. 2015;38(5):855-861.
  141. Wang Q#, Jia J*, Qin W, Wu L, Li D, Wang Q, Li H. A Novel AβPP M722K Mutation Affects Amyloid-β Secretion and Tau Phosphorylation and May Cause Early-Onset Familial Alzheimer’s Disease in Chinese Individuals. J Alzheimers Dis. 2015;47(1):157-165.
  142. Tang Y#, Wang X#, Jia J#. Mercury poisoning presenting as sporadic Creutzfeldt-Jakob disease: a case report. Ann Intern Med. 2015;162(6):462-463.
  143. Song H#, Long H, Zuo X, Yu C, Liu B, Wang Z, Wang Q, Wang F, Han Y, Jia J*. APOE Effects on Default Mode Network in Chinese Cognitive Normal Elderly: Relationship with Clinical Cognitive Performance. PLoS One. 2015;10(7):e0133179.
  144. Qin W#, Jia X, Wang F, Zuo X, Wu L, Zhou A, Li D, Min B, Wei C, Tang Y, Xing Y, Dong X, Wang Q, Gao Y, Li Y, Jia J*. Elevated plasma angiogenesis factors in Alzheimer’s disease. J Alzheimers Dis. 2015;45(1):245-252.
  145. Peng M#, Jia J*, Qin W. Plasma gelsolin and matrix metalloproteinase 3 as potential biomarkers for Alzheimer disease. Neurosci Lett. 2015;595:116-121.
  146. Meng R#, Ding Y, Asmaro K, Brogan D, Meng L, Sui M, Shi J, Duan Y, Sun Z, Yu Y, Jia J, Ji X*. Ischemic Conditioning Is Safe and Effective for Octo- and Nonagenarians in Stroke Prevention and Treatment. Neurotherapeutics. 2015;12(3):667-677.
  147. Mei Y#, Jiang C#, Wan Y, Lv J, Jia J, Wang X, Yang X*, Tong Z*. Aging-associated formaldehyde-induced norepinephrine deficiency contributes to age-related memory decline. Aging Cell. 2015;14(4):659-668.
  148. Liu R#, Tian T, Jia J*. Characterization of the interactions between β-amyloid peptide and the membranes of human SK-N-SH cells. FEBS Lett. 2015;589(15):1929-1934.
  149. Liu J#*, Wang L, Jia J. Peroxisome proliferator-activated receptor-gamma agonists for Alzheimer’s disease and amnestic mild cognitive impairment: a systematic review and meta-analysis. Drugs Aging. 2015;32(1):57-65.
  150. Li H#*, Jia J, Xu M, Zhang L. Changes in the blood-nerve barrier after sciatic nerve cold injury: indications supporting early treatment. Neural Regen Res. 2015;10(3):419-424.
  151. Jia B#, Liu Z, Min B, Wang Z, Zhou A, Li Y, Qiao H*, Jia J*. The Effects of Acupuncture at Real or Sham Acupoints on the Intrinsic Brain Activity in Mild Cognitive Impairment Patients. Evid Based Complement Alternat Med. 2015;2015:529675.
  152. Huang Y#, Yang S, Jia J*. Factors related to long-term post-stroke cognitive impairment in young adult ischemic stroke. Med Sci Monit. 2015;21:654-660.
  153. Huang X#, Fan C#, Wu J, Ye J, Zhan S, Song H, Liu A, Su Y, Jia J*. Clinical analysis on anti-N-methyl-D-aspartate receptor encephalitis cases: Chinese experience. Int J Clin Exp Med. 2015;8(10):18927-18935.
  154. Huang X#, Du X#, Song H, Zhang Q, Jia J, Xiao T, Wu J*. Cognitive impairments associated with corpus callosum infarction: a ten cases study. Int J Clin Exp Med. 2015;8(11):21991-21998.
  155. Huang Q#, Ma Q#, Jia J, Feng J, Cheng W, Chang H, Wu J*. Referral leads to prehospital delay of intravenous thrombolysis for acute ischemic stroke in Beijing. Int J Stroke. 2015;10(7):E80-81.
  156. Huang Q#, Ma Q#, Feng J, Cheng W, Jia J, Song H, Chang H, Wu J*. Factors Associated with In-Hospital Delay in Intravenous Thrombolysis for Acute Ischemic Stroke: Lessons from China. PLoS One. 2015;10(11):e0143145.
  157. Gauthier S#*, Proano JV, Jia J, Froelich L, Vester JC, Doppler E. Cerebrolysin in mild-to-moderate Alzheimer’s disease: a meta-analysis of randomized controlled clinical trials. Dement Geriatr Cogn Disord. 2015;39(5-6):332-347.
  158. Zhao Z#, Lu J, Jia X, Chao W, Han Y, Jia J, Li K*. Selective changes of resting-state brain oscillations in aMCI: an fMRI study using ALFF. Biomed Res Int. 2014;2014:920902.
  159. Zhang Y#, Lu L#, Jia J*, Jia L, Geula C, Pei J, Xu Z, Qin W, Liu R, Li D, Pan N. A lifespan observation of a novel mouse model: in vivo evidence supports aβ oligomer hypothesis. PLoS One. 2014;9(1):e85885.
  160. Zhang J#, Peng M, Jia J*. Plasma amyloid-β oligomers and soluble tumor necrosis factor receptors as potential biomarkers of AD. Curr Alzheimer Res. 2014;11(4):325-331.
  161. Yin L#*, Liu J#, Dong H, Xu E, Qiao Y, Wang L, Zhang L, Jia J, Li L*, Geng X. Autophagy-related gene16L2, a potential serum biomarker of multiple sclerosis evaluated by bead-based proteomic technology. Neurosci Lett. 2014;562:34-38.
  162. Xue X#, Zhang M, Lin Y, Xu E*, Jia J. Association between the SORL1 rs2070045 polymorphism and late-onset Alzheimer’s disease: interaction with the ApoE genotype in the Chinese Han population. Neurosci Lett. 2014;559:94-98.
  163. Wu L#, Soder RB, Schoemaker D, Carbonnell F, Sziklas V, Rowley J, Mohades S, Fonov V, Bellec P, Dagher A, Shmuel A, Jia J, Gauthier S, Rosa-Neto P*. Resting state executive control network adaptations in amnestic mild cognitive impairment. J Alzheimers Dis. 2014;40(4):993-1004.
  164. Wang X#, Yang Y, Wang X, Li C*, Jia J. A novel KIAA0196 (SPG8) mutation in a Chinese family with spastic paraplegia. Chin Med J (Engl). 2014;127(10):1987-1989.
  165. Wang S#, Jia J*. Oxymatrine attenuates diabetes-associated cognitive deficits in rats. Acta Pharmacol Sin. 2014;35(3):331-338.
  166. Sun Y#, Wang Y, Ji X, Wu X, Zhao Y, Ding Y, Hussain M, Yu F, Zhao W, Jia J*. A Randomized Trial of Chinese Diaoshi Jifa on Treatment of Dizziness in Meniere’s Disease. Evid Based Complement Alternat Med. 2014;2014:521475.
  167. Sun Y#, Ji X, Mao X, Xie L, Jia J, Galvan V, Greenberg DA, Jin K*. Differential activation of mTOR complex 1 signaling in human brain with mild to severe Alzheimer’s disease. J Alzheimers Dis. 2014;38(2):437-444.
  168. Sun J#, Song F, Wang J, Han G, Bai Z, Xie B, Feng X, Jia J, Duan Y*, Lei H. Hidden risk genes with high-order intragenic epistasis in Alzheimer’s disease. J Alzheimers Dis. 2014;41(4):1039-1056.
  169. Pei J#, Giron MS, Jia J, Wang H*. Dementia studies in Chinese populations. Neurosci Bull. 2014;30(2):207-216.
  170. Lin F#, Jia J*, Qin W. Enhancement of β-amyloid oligomer accumulation after intracerebroventricular injection of streptozotocin, which involves central insulin signaling in a transgenic mouse model. Neuroreport. 2014;25(16):1289-1295.
  171. Liang J#, Jia J*. Dysfunctional autophagy in Alzheimer’s disease: pathogenic roles and therapeutic implications. Neurosci Bull. 2014;30(2):308-316.
  172. Liang J#, Li F, Wei C, Song H, Wu L, Tang Y, Jia J*. Rationale and design of a multicenter, phase 2 clinical trial to investigate the efficacy of traditional Chinese medicine SaiLuoTong in vascular dementia. J Stroke Cerebrovasc Dis. 2014;23(10):2626-2634.
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  174. Jia J#*, Wang F, Wei C, Zhou A, Jia X, Li F, Tang M, Chu L, Zhou Y, Zhou C, Cui Y, Wang Q, Wang W, Yin P, Hu N, Zuo X, Song H, Qin W, Wu L, Li D, Jia L, Song J, Han Y, Xing Y, Yang P, Li Y, Qiao Y, Tang Y, Lv J, Dong X. The prevalence of dementia in urban and rural areas of China. Alzheimers Dement. 2014;10(1):1-9.
  175. Huang X#, Fan C, Jia J, Wang L, Li X, Wu Y, Deng Y, Wu J*. The effect of transient ischemic attack clinical pathway. J Neuropsychiatry Clin Neurosci. 2014;26(4):386-391.
  176. Huang Q#, Ma Q, Jia J, Wu J*. Intravenous thrombolysis for minor stroke and rapidly improving symptoms: a quantitative overview. Neurol Sci. 2014;35(9):1321-1328.
  177. Hu Z#, Wu L, Jia J, Han Y*. Advances in longitudinal studies of amnestic mild cognitive impairment and Alzheimer’s disease based on multi-modal MRI techniques. Neurosci Bull. 2014;30(2):198-206.
  178. Cong L#, Jia J*, Qin W, Ren Y, Sun Y*. Genome-wide analysis of DNA methylation in an APP/PS1 mouse model of Alzheimer’s disease. Acta Neurol Belg. 2014;114(3):195-206.
  179. Zhang J#, Jia J*, Qin W, Wang S. Combination of plasma tumor necrosis factor receptors signaling proteins, beta-amyloid and apolipoprotein E for the detection of Alzheimer’s disease. Neurosci Lett. 2013;541:99-104.
  180. Yuan Q#, Wang F, Xue S, Jia J*. Association of polymorphisms in the LRP1 and A2M genes with Alzheimer’s disease in the northern Chinese Han population. J Clin Neurosci. 2013;20(2):253-256.
  181. Xue S#*, Ma Q, Ma X, Jia J. Isolated cortical vein thrombosis: a widely variable clinicoradiological spectrum. Eur Neurol. 2013;69(6):331-335.
  182. Xu M#*, Da Y, Liu L, Wang F, Jia J. Giant axonal neuropathy caused by a novel compound heterozygous mutation in the gigaxonin gene. J Child Neurol. 2013;28(10):1316-1319.
  183. Xing Y#, Qin W, Li F, Jia X, Jia J*. Associations between sex hormones and cognitive and neuropsychiatric manifestations in vascular dementia (VaD). Arch Gerontol Geriatr. 2013;56(1):85-90.
  184. Xing Y#, Jia J*, Ji X, Tian T. Estrogen associated gene polymorphisms and their interactions in the progress of Alzheimer’s disease. Prog Neurobiol. 2013;111:53-74.
  185. Wang Y#*, Wang Y, Zhao X, Liu L, Wang D, Wang C, Wang C, Li H, Meng X, Cui L, Jia J, Dong Q, Xu A, Zeng J, Li Y, Wang Z, Xia H, Johnston SC, Investigators C. Clopidogrel with aspirin in acute minor stroke or transient ischemic attack. N Engl J Med. 2013;369(1):11-19.
  186. Wang L#, Jia J*, Wu L. The relationship between cognitive impairment and cerebral blood flow changes after transient ischaemic attack. Neurol Res. 2013;35(6):580-585.
  187. Wang J#, Zuo X, Dai Z, Xia M, Zhao Z, Zhao X, Jia J, Han Y, He Y*. Disrupted functional brain connectome in individuals at risk for Alzheimer’s disease. Biol Psychiatry. 2013;73(5):472-481.
  188. Mi T#, Han C, Wang Y, Ma H, Jia J, Ding Y, Esmail F, Chen J, Peng L, Xu J, Sun Y*. Acute toxic leukoencephalopathy in migrant workers exposed to organic solvents in construction materials. Occup Environ Med. 2013;70(6):435-436.
  189. Liu J#, Yin C#, Xia S, Jia L, Guo Y, Zhao Z, Li X*, Han Y*, Jia J. White matter changes in patients with amnestic mild cognitive impairment detected by diffusion tensor imaging. PLoS One. 2013;8(3):e59440.
  190. Liang F#, Jia J*, Wang S, Qin W, Liu G. Decreased plasma levels of soluble low density lipoprotein receptor-related protein-1 (sLRP) and the soluble form of the receptor for advanced glycation end products (sRAGE) in the clinical diagnosis of Alzheimer’s disease. J Clin Neurosci. 2013;20(3):357-361.
  191. Li Z#, Yang D, Lu Y, Liu D, Jia J, Jonas JB, Wang N*. Intracranial hypotension and co-existent normal-pressure glaucoma: the Beijing intracranial and intraocular pressure study. Chin Med J (Engl). 2013;126(8):1588-1589.
  192. Li F#, Wang F, Jia J*. Evaluating the prevalence of dementia in hospitalized older adults and effects of comorbid dementia on patients’ hospital course. Aging Clin Exp Res. 2013;25(4):393-401.
  193. Leak RK#, Zhang L, Luo Y, Li P, Zhao H, Liu X, Ling F, Jia J, Chen J, Ji X*. Peroxiredoxin 2 battles poly(ADP-ribose) polymerase 1- and p53-dependent prodeath pathways after ischemic injury. Stroke. 2013;44(4):1124-1134.
  194. Huang Y#, Jia J*. Corpus callosum hematoma secondary to cerebral venous malformation presenting as alien hand syndrome. Neurocase. 2013;19(4):377-381.
  195. Huang L#, Jia J*, Liu R. Decreased serum levels of the angiogenic factors VEGF and TGF-β1 in Alzheimer’s disease and amnestic mild cognitive impairment. Neurosci Lett. 2013;550:60-63.
  196. Deng T#, Jia J*, Zhang T, Guo D, Yang L. Cortical versus non-cortical lesions affect expression of Babinski sign. Neurol Sci. 2013;34(6):855-859.
  197. Da Y#*, Wang M, Li Y, Lu Y, Jia J*. An unusual case with myotonia. Kaohsiung J Med Sci. 2013;29(3):172-175.
  198. Da Y#, Zhang X, Li F, Yang X, Zhang X, Jia J*. Posterior reversible encephalopathy syndrome in a leber hereditary optic neuropathy patient with mitochondrial DNA 11778G>A point mutation. J Neuroophthalmol. 2013;33(3):276-278.
  199. Cheng D#, Zhou A#, Yu X, Chen C, Jia J, Zhou X*. Quantifier processing can be dissociated from numerical processing: evidence from semantic dementia patients. Neuropsychologia. 2013;51(11):2172-2183.
  200. Zhang Z#, Deng L, Yu H, Shi Y, Bai F, Xie C, Yuan Y, Jia J, Zhang Z*. Association of angiotensin-converting enzyme functional gene I/D polymorphism with amnestic mild cognitive impairment. Neurosci Lett. 2012;514(1):131-135.
  201. Yuan Q#, Chu C#, Jia J*. Association studies of 19 candidate SNPs with sporadic Alzheimer’s disease in the North Chinese Han population. Neurol Sci. 2012;33(5):1021-1028.
  202. Yi L#, Wang J#, Jia L, Zhao Z, Lu J, Li K, Jia J, He Y, Jiang C*, Han Y*. Structural and functional changes in subcortical vascular mild cognitive impairment: a combined voxel-based morphometry and resting-state fMRI study. PLoS One. 2012;7(9):e44758.
  203. Xing Y#, Wei C, Chu C, Zhou A, Li F, Wu L, Song H, Zuo X, Wang F, Qin W, Li D, Tang Y, Jia XF, Jia J*. Stage-specific gender differences in cognitive and neuropsychiatric manifestations of vascular dementia. Am J Alzheimers Dis Other Demen. 2012;27(6):433-438.
  204. Xing Y#, Qin W, Li F, Jia XF, Jia J*. Apolipoprotein E ε4 status modifies the effects of sex hormones on neuropsychiatric symptoms of Alzheimer’s disease. Dement Geriatr Cogn Disord. 2012;33(1):35-42.
  205. Wu L#, Rowley J, Mohades S, Leuzy A, Dauar MT, Shin M, Fonov V, Jia J, Gauthier S, Rosa-Neto P*. Dissociation between brain amyloid deposition and metabolism in early mild cognitive impairment. PLoS One. 2012;7(10):e47905.
  206. Wu L#, Rosa-Neto P, Hsiung GY, Sadovnick AD, Masellis M, Black SE, Jia J, Gauthier S*. Early-onset familial Alzheimer’s disease (EOFAD). Can J Neurol Sci. 2012;39(4):436-445.
  207. Wu J#, Jia L, Jia J*. Awareness of secondary stroke prevention guidelines among neurologists in China: a cross-sectional online survey. Chin Med J (Engl). 2012;125(11):1867-1870.
  208. Wang Y#, Cheng Z, Qin W, Jia J*. Val97Leu mutant presenilin-1 induces tau hyperphosphorylation and spatial memory deficit in mice and the underlying mechanisms. J Neurochem. 2012;121(1):135-145.
  209. Wang X#, Sun W, Yang Y, Jia J, Li C*. A clinical and gene analysis of late-onset combined methylmalonic aciduria and homocystinuria, cblC type, in China. J Neurol Sci. 2012;318(1-2):155-159.
  210. Wang S#, Song J, Tan M, Albers KM, Jia J*. Mitochondrial fission proteins in peripheral blood lymphocytes are potential biomarkers for Alzheimer’s disease. Eur J Neurol. 2012;19(7):1015-1022.
  211. Wang M#, Da Y*, Cai H, Lu Y, Wu L, Jia J. Telbivudine myopathy in a patient with chronic hepatitis B. Int J Clin Pharm. 2012;34(3):422-425.
  212. Wang F#, Shu C#, Jia L, Zuo X, Zhang Y, Zhou A, Qin W, Song H, Wei C, Zhang F, Hong Z, Tang M, Wang D*, Jia J*. Exploration of 16 candidate genes identifies the association of IDE with Alzheimer’s disease in Han Chinese. Neurobiol Aging. 2012;33(5):1014.e1011-1019.
  213. Tang Y#, Xing Y#, Lin MT, Zhang J, Jia J*. Hashimoto’s encephalopathy cases: Chinese experience. BMC Neurol. 2012;12:60.
  214. Tan M#, Wang S, Song J, Jia J*. Combination of p53(ser15) and p21/p21(thr145) in peripheral blood lymphocytes as potential Alzheimer’s disease biomarkers. Neurosci Lett. 2012;516(2):226-231.
  215. Song J#, Wang S, Tan M, Jia J*. G1/S checkpoint proteins in peripheral blood lymphocytes are potentially diagnostic biomarkers for Alzheimer’s disease. Neurosci Lett. 2012;526(2):144-149.
  216. Meng R#, Asmaro K, Meng L, Liu Y, Ma C, Xi C, Li G, Ren C, Luo Y, Ling F, Jia J, Hua Y, Wang X, Ding Y, Lo EH, Ji X*. Upper limb ischemic preconditioning prevents recurrent stroke in intracranial arterial stenosis. Neurology. 2012;79(18):1853-1861.
  217. Lu Y#, Li X#, Wang M, Li X, Zhang F, Li Y, Zhang M, Da Y*, Yu J*, Jia J. A novel autosomal dominant inclusion body myopathy linked to 7q22.1-31.1. PLoS One. 2012;7(6):e39288.
  218. Liu J#, Yin L#, Dong H, Xu E, Zhang L, Qiao Y, Liu Y, Li L*, Jia J*. Decreased serum levels of nucleolin protein fragment, as analyzed by bead-based proteomic technology, in multiple sclerosis patients compared to controls. J Neuroimmunol. 2012;250(1-2):71-76.
  219. Li Z#, Yang Y#, Lu Y, Liu D, Xu E, Jia J, Yang D, Zhang X, Yang H, Ma D, Wang N*. Intraocular pressure vs intracranial pressure in disease conditions: a prospective cohort study (Beijing iCOP study). BMC Neurol. 2012;12:66.
  220. Li F#, Jia X, Jia J*. The Informant Questionnaire on Cognitive Decline in the Elderly individuals in screening mild cognitive impairment with or without functional impairment. J Geriatr Psychiatry Neurol. 2012;25(4):227-232.
  221. Ji X#, Jia L, Jia J*, Qi L. Genetic association of urokinase-type plasminogen activator gene rs2227564 site polymorphism with sporadic Alzheimer’s disease in the Han Chinese population. Neural Regen Res. 2012;7(30):2377-2383.
  222. Han Y#*, Lui S#, Kuang W, Lang Q, Zou L, Jia J. Anatomical and functional deficits in patients with amnestic mild cognitive impairment. PLoS One. 2012;7(2):e28664.
  223. Han Y#, Jia J*, Jia XF, Qin W, Wang S. Combination of plasma biomarkers and clinical data for the detection of sporadic Alzheimer’s disease. Neurosci Lett. 2012;516(2):232-236.
  224. Han C#, Wang Y, Jia J, Ji X, Fredrickson V, Ding Y, Sun W, Xu J, Sun Y*. Bickerstaff’s brainstem encephalitis, Miller Fisher syndrome and Guillain-Barre syndrome overlap in an asthma patient with negative anti-ganglioside antibodies. BMC Res Notes. 2012;5:295.
  225. Geng X#, Ren C, Wang T, Fu P, Luo Y, Liu X, Yan F, Ling F, Jia J, Du H, Ji X*, Ding Y. Effect of remote ischemic postconditioning on an intracerebral hemorrhage stroke model in rats. Neurol Res. 2012;34(2):143-148.
  226. Gauthier S#*, Wu L, Rosa-Neto P, Jia J. Prevention strategies for Alzheimer’s disease. Transl Neurodegener. 2012;1(1):13.
  227. Bai F#, Shi Y, Yuan Y, Wang Y, Yue C, Teng Y, Wu D, Zhang Z, Jia J*, Zhang Z*. Altered self-referential network in resting-state amnestic type mild cognitive impairment. Cortex. 2012;48(5):604-613.
  228. Zhang Z#, Deng L, Bai F, Shi Y, Yu H, Yuan Y, Jiang T, Jia J, Zhang Z*. ACE I/D polymorphism affects cognitive function and gray-matter volume in amnestic mild cognitive impairment. Behav Brain Res. 2011;218(1):114-120.
  229. Zhan S#*, Cai GQ, Zheng A, Wang Y, Jia J, Fang H, Yang Y, Hu M, Ding Q. Tumor necrosis factor-alpha regulates the Hypocretin system via mRNA degradation and ubiquitination. Biochim Biophys Acta-molecular basis of disease. 2011;1812(4):565-571.
  230. Tang Y#, Chu C#, Lin MT, Wei G, Zhang X, Da Y, Huang H, Jia J*. Hashimoto’s encephalopathy mimicking spinocerebellar ataxia. J Neurol. 2011;258(9):1705-1707.
  231. Shi F#*, Jia J*. Neurology and neurologic practice in China. Neurology. 2011;77(22):1986-1992.
  232. Qin W#, Jia L, Zhou A, Zuo X, Cheng Z, Wang F, Shi F, Jia J*. The -980C/G polymorphism in APH-1A promoter confers risk of Alzheimer’s disease. Aging Cell. 2011;10(4):711-719.
  233. Lu J#, Li D, Li F, Zhou A, Wang F, Zuo X, Jia X, Song H, Jia J*. Montreal cognitive assessment in detecting cognitive impairment in Chinese elderly individuals: a population-based study. J Geriatr Psychiatry Neurol. 2011;24(4):184-190.
  234. Lin H#*, Huang Y, Wang Y, Jia J. Spatiotemporal profile of N-cadherin expression in the mossy fiber sprouting and synaptic plasticity following seizures. Mol Cell Biochem. 2011;358(1-2):201-205.
  235. Ji R#*, Jia J, Ma X, Wu J, Zhang Y, Xu L. Genetic variants in the promoter region of the ALOX5AP gene and susceptibility of ischemic stroke. Cerebrovasc Dis. 2011;32(3):261-268.
  236. Han Y#, Wang J, Zhao Z, Min B, Lu J, Li K, He Y, Jia J*. Frequency-dependent changes in the amplitude of low-frequency fluctuations in amnestic mild cognitive impairment: a resting-state fMRI study. Neuroimage. 2011;55(1):287-295.
  237. Dong H#, Liu Z#, Tang Y, Lu Y, Wang Q, Jia J*. Recurrent Fisher-Bickerstaff syndrome: report of a Chinese case. Chin Med J (Engl). 2011;124(17):2786-2788.
  238. Cong L#, Jia J*. Promoter polymorphisms which regulate ADAM9 transcription are protective against sporadic Alzheimer’s disease. Neurobiol Aging. 2011;32(1):54-62.
  239. Bai F#, Liao W, Watson DR, Shi Y, Yuan Y, Cohen AD, Xie C, Wang Y, Yue C, Teng Y, Wu D, Jia J*, Zhang Z*. Mapping the altered patterns of cerebellar resting-state function in longitudinal amnestic mild cognitive impairment patients. J Alzheimers Dis. 2011;23(1):87-99.
  240. Bai F#, Liao W, Watson DR, Shi Y, Wang Y, Yue C, Teng Y, Wu D, Yuan Y, Jia J, Zhang Z*. Abnormal whole-brain functional connection in amnestic mild cognitive impairment patients. Behav Brain Res. 2011;216(2):666-672.
  241. Zhou X#, Jia J*. P53-mediated G(1)/S checkpoint dysfunction in lymphocytes from Alzheimer’s disease patients. Neurosci Lett. 2010;468(3):320-325.
  242. Zhang Z#, Deng L, Bai F, Shi Y, Yu H, Yuan Y, Wang K, Jiang T, Jia J, Zhang Z*. Alteration of resting brain function by genetic variation in angiotensin converting enzyme in amnestic-type mild cognitive impairment of Chinese Han. Behav Brain Res. 2010;208(2):619-625.
  243. Yuan Q#, Jia J*. Reduced cognitive function in Chinese patients with early amyotrophic lateral sclerosis and associated factors. Int J Neurosci. 2010;120(10):641-646.
  244. Yu G#, Jia J*. Is there an association of regulatory region polymorphism in the alpha-1-antichymotrypsin gene with sporadic Alzheimer’s disease in the northern Han-Chinese population? J Clin Neurosci. 2010;17(6):766-769.
  245. Xue S#, Jia J*. Cardioembolic occlusion of the internal carotid artery presented with infarction in the posterior cerebral artery territory. Chin Med J (Engl). 2010;123(22):3375-3376.
  246. Wang S#, Jia J*. Promoter polymorphisms which modulate BACE1 expression are associated with sporadic Alzheimer’s disease. Am J Med Genet B Neuropsychiatr Genet. 2010;153b(1):159-166.
  247. Wang M#, Song H#, Jia J*. Interleukin-6 receptor gene polymorphisms were associated with sporadic Alzheimer’s disease in Chinese Han. Brain Res. 2010;1327:1-5.
  248. Wang M#, Li Y, Lu Y, Zuo X, Wang F, Zhang Z, Jia J*. The relationship between ADAM17 promoter polymorphisms and sporadic Alzheimer’s disease in a Northern Chinese Han population. J Clin Neurosci. 2010;17(10):1276-1279.
  249. Wang M#, Jia J*. The interleukin-6 gene -572C/G promoter polymorphism modifies Alzheimer’s risk in APOE epsilon 4 carriers. Neurosci Lett. 2010;482(3):260-263.
  250. Tang Y#, Wang X*, Ding Y, Li C, Jia J. Longitudinal lesion of the spinal cord in a patient with Vogt-Koyanagi-Harada disease. J Neurol Neurosurg Psychiatry. 2010;81(8):941-942.
  251. Song H#, Jia L, Zuo X, Jia J*. Association between haplotype -88G/25G in A2M with Alzheimer’s disease. Neurosci Lett. 2010;479(2):143-145.
  252. Lu Y#*, Li Z, Zhang X, Ming B, Jia J, Wang R, Ma D. Retinal nerve fiber layer structure abnormalities in early Alzheimer’s disease: evidence in optical coherence tomography. Neurosci Lett. 2010;480(1):69-72.
  253. Liu Z#, Jia L, Piao Y, Lu D, Wang F, Lv H, Lu Y, Jia J*. Creutzfeldt-Jakob disease with PRNP G114V mutation in a Chinese family. Acta Neurol Scand. 2010;121(6):377-383.
  254. Li S#, Guo X*, Wu J, Jia J. Migraine-induced stroke with risk factors–involving two cerebral artery territories. Headache. 2010;50(7):1203-1206.
  255. Han D#*, Wang Y, Li H, Jia J. Northern Chinese Han populations with sporadic Alzheimer’s disease and the role of urokinase-type plasminogen activator gene promoter polymorphisms. Neural Regeneration Research. 2010;5(2):150-155.
  256. Zuo X#, Jia J*. Promoter polymorphisms which modulate insulin degrading enzyme expression may increase susceptibility to Alzheimer’s disease. Brain Res. 2009;1249:1-8.
  257. Zhou A#, Jia J*. Different cognitive profiles between mild cognitive impairment due to cerebral small vessel disease and mild cognitive impairment of Alzheimer’s disease origin. J Int Neuropsychol Soc. 2009;15(6):898-905.
  258. Zhou A#, Jia J*. A screen for cognitive assessments for patients with vascular cognitive impairment no dementia. Int J Geriatr Psychiatry. 2009;24(12):1352-1357.
  259. Yuan Q#, Zuo X, Jia J*. Association between promoter polymorphisms of vascular endothelial growth factor gene and sporadic Alzheimer’s disease among Northern Chinese Han. Neurosci Lett. 2009;457(3):133-136.
  260. Yu Y#, Jia J*. Lack of association between the polymorphisms of beta-site APP-cleaving enzyme 2 (BACE2) 5′-flanking region and sporadic Alzheimer’s disease. Brain Res. 2009;1257:10-15.
  261. Xue S#, Jia L, Jia J*. Association between somatostatin gene polymorphisms and sporadic Alzheimer’s disease in Chinese population. Neurosci Lett. 2009;465(2):181-183.
  262. Xu E#*, Tang Y, Li D, Jia J. Polymorphism of HD and UCHL-1 genes in Huntington’s disease. J Clin Neurosci. 2009;16(11):1473-1477.
  263. Wang Y#, Jia J*. Association between promoter polymorphisms in anterior pharynx-defective-1a and sporadic Alzheimer’s disease in the North Chinese Han population. Neurosci Lett. 2009;455(2):101-104.
  264. Sun W#, Jia J*. The +347 C promoter allele up-regulates MAPT expression and is associated with Alzheimer’s disease among the Chinese Han. Neurosci Lett. 2009;450(3):340-343.
  265. Shi Y#, Zhou H, Zhang Z*, Yu H, Bai F, Yuan Y, Deng L, Jia J. Association of the LRP1 gene and cognitive performance with amnestic mild cognitive impairment in elderly Chinese. Int Psychogeriatr. 2009;21(6):1072-1080.
  266. Ma Z#, Han D#, Zuo X, Wang F, Jia J*. Association between promoter polymorphisms of the nicastrin gene and sporadic Alzheimer’s disease in North Chinese Han population. Neurosci Lett. 2009;458(3):136-139.
  267. Lu Y#, Wang M, Liu Z, Wang F, Da Y, Jia J*. No association between the promoter polymorphisms of PAI-1 gene and sporadic Alzheimer’s disease in Chinese Han population. Neurosci Lett. 2009;455(2):97-100.
  268. Jiang H#, Jia J*. Association between NR2B subunit gene (GRIN2B) promoter polymorphisms and sporadic Alzheimer’s disease in the North Chinese population. Neurosci Lett. 2009;450(3):356-360.
  269. Bai F#, Zhang Z*, Watson DR, Yu H, Shi Y, Yuan Y, Qian Y, Jia J. Abnormal integrity of association fiber tracts in amnestic mild cognitive impairment. J Neurol Sci. 2009;278(1-2):102-106.
  270. Zhou Y#, Jia J*. Effect of acupuncture given at the HT 7, ST 36, ST 40 and KI 3 acupoints on various parts of the brains of Alzheimer’ s disease patients. Acupunct Electrother Res. 2008;33(1-2):9-17.
  271. Zhou W#, Xu D#, Peng X, Zhang Q, Jia J, Crutcher KA*. Meta-analysis of APOE4 allele and outcome after traumatic brain injury. J Neurotrauma. 2008;25(4):279-290.
  272. Zhou A#, Jia J*. The value of the clock drawing test and the mini-mental state examination for identifying vascular cognitive impairment no dementia. Int J Geriatr Psychiatry. 2008;23(4):422-426.
  273. Zhang W#, Jia J*. Green tea extract, epigallocatechin-3-gallate, inhibits the growth and invasive ability of human glioma cells. Mol Med Rep. 2008;1(5):735-739.
  274. Wu L#, Wang X*, Wei H, Li C, Jia J. Diffuse cortical lesions with hemorrhage in cerebral Whipple’s disease. Clin Neurol Neurosurg. 2008;110(1):83-87.
  275. Wei C#, Jia J*, Liang P, Guan Y. Ginsenoside Rg1 attenuates beta-amyloid-induced apoptosis in mutant PS1 M146L cells. Neurosci Lett. 2008;443(3):145-149.
  276. Qin W#, Jia J*. Down-regulation of insulin-degrading enzyme by presenilin 1 V97L mutant potentially underlies increased levels of amyloid beta 42. Eur J Neurosci. 2008;27(9):2425-2432.
  277. Ma B#, Zhang Y, Wu D, Jia J, Xu W, Luo Y*. Affinity-purification of fibrinogenase with high proteolytic activity from Agkistrodon halys (Chinese) Venom. Arch Pharm Res. 2008;31(9):1129-1136.
  278. Lv H#, Jia L, Jia J*. Promoter polymorphisms which modulate APP expression may increase susceptibility to Alzheimer’s disease. Neurobiol Aging. 2008;29(2):194-202.
  279. Liu Z#, Jia L, Ye J, Zhang X, Song H, Lv H, Wang F, Dong X, Jia J*. PRNP mutations in a series of apparently sporadic neurodegenerative dementias in China. Am J Med Genet B Neuropsychiatr Genet. 2008;147b(6):938-944.
  280. Liu Z#, Jia J*. The association of the regulatory region of the presenilin-2 gene with Alzheimer’s disease in the Northern Han Chinese population. J Neurol Sci. 2008;264(1-2):38-42.
  281. Fang B#, Jia J*. Human neuroblastoma cells transfected with two Chinese presenilin 1 mutations are sensitized to trophic factor withdrawal and protected by insulin-like growth factor-1. Chin Med J (Engl). 2008;121(10):910-915.
  282. Chen Y#, Jia L, Wei C, Wang F, Lv H, Jia J*. Association between polymorphisms in the apolipoprotein D gene and sporadic Alzheimer’s disease. Brain Res. 2008;1233:196-202.
  283. Wang F#, Jia J*. Polymorphisms of cholesterol metabolism genes CYP46 and ABCA1 and the risk of sporadic Alzheimer’s disease in Chinese. Brain Res. 2007;1147:34-38.
  284. Liu Z#*, Jia J. Novel human pathological mutations. Gene symbol: PRNP. Disease: dementia. Hum Genet. 2007;122(5):545.
  285. Jia L#, Ye J, L VH, Wang W, Zhou C, Zhang X, Xu J, Wang L, Jia J*. Genetic association between polymorphisms of Pen2 gene and late onset Alzheimer’s disease in the North Chinese population. Brain Res. 2007;1141:10-14.
  286. Da Y#, Jia J*. Study of antibodies to PMP22, IL-6 and TNF-alpha concentrations in serum in a CMTX1 family. Neurosci Lett. 2007;424(2):73-77.
  287. Xue S#, Jia L, Jia J*. Hypoxia and reoxygenation increased BACE1 mRNA and protein levels in human neuroblastoma SH-SY5Y cells. Neurosci Lett. 2006;405(3):231-235.
  288. Xue S#, Jia J*. Genetic association between Ubiquitin Carboxy-terminal Hydrolase-L1 gene S18Y polymorphism and sporadic Alzheimer’s disease in a Chinese Han population. Brain Res. 2006;1087(1):28-32.
  289. Mao W#, Yang J, Wang M, Wang Y*, Wang D, Zhu L, Jia J. Event-related potential N270 in detecting cognitive impairment in patients with transient ischemic attack. J Clin Neurophysiol. 2006;23(6):559-564.
  290. Liu L#*, Dong W, Ji X, Chen L, Chen L, He W, Jia J. A new method of noninvasive brain-edema monitoring in stroke: cerebral electrical impedance measurement. Neurol Res. 2006;28(1):31-37.
  291. Jia L#, Zhou C, Lv H, Wang W, Ye J, Zhang X, Zhou W, Xu J, Wang L, Jia J*. Association between presenilin 1 intronic polymorphism and late onset Alzheimer’s disease in the North Chinese population. Brain Res. 2006;1116(1):201-205.
  292. Ji X#, Meng R, Zhou J, Ling F, Jia J*. Dynamic change of coagulation and anticoagulation markers of patients with acute cerebral infarction during intravenous urokinase thrombolysis. Neurol Res. 2006;28(1):46-49.
  293. Fang B#, Jia L, Jia J*. Chinese Presenilin-1 V97L mutation enhanced Abeta42 levels in SH-SY5Y neuroblastoma cells. Neurosci Lett. 2006;406(1-2):33-37.
  294. Zhou J#*, Meng R, Sui X, Meng L, Jia J, Yang B. Effects of administration styles of arsenic trioxide on intracellular arsenic concentration, cell differentiation and apoptosis. Haematologica. 2005;90(9):1277-1279.
  295. Jia J#*, Meng R, Sun Y, Sun WJ, Ji X, Jia L. Cerebrospinal fluid tau, Abeta1-42 and inflammatory cytokines in patients with Alzheimer’s disease and vascular dementia. Neurosci Lett. 2005;383(1-2):12-16.
  296. Jia J#*, Xu E, Shao Y, Jia J, Sun Y, Li D. One novel presenilin-1 gene mutation in a Chinese pedigree of familial Alzheimer’s disease. J Alzheimers Dis. 2005;7(2):119-124; discussion 173-180.
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  298. Jia J#, Pollock M*. Treatment of rats with experimental allergic neuritis using high dose immunoglobulin. Chin Med J (Engl). 2000;113(12):1096-1099.
  299. Jia J#, Jia JM, Pollock M*. The synergistic enhancement of pathology in intermittently cooled nerve. Chin Med J (Engl). 2000;113(3):241-245.
  300. Jia J#, Pollock M*. Cold nerve injury is enhanced by intermittent cooling. Muscle Nerve. 1999;22(12):1644-1652.
  301. Jia J#, Pollock M*, Jia JM. Cold injury to nerves is not due to ischaemia alone. Brain. 1998;121 ( Pt 5):989-1001.
  302. Jia J#, Pollock M*. The pathogenesis of non-freezing cold nerve injury. Observations in the rat. Brain. 1997;120 ( Pt 4):631-646.